Yeong Kozera
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease that primarily affects women. The role of sex hormones, such as oestrogen and progesterone, is unknown, but changes in hormone levels may play a role in disease activity in many patients. Women with HS should be given special clinical considerations, especially during pregnancy, childbirth, breastfeeding, and menopause. Current knowledge gaps in HS include the disease's cumulative impact over an individual's lifetime, as well as the mechanistic role of sex hormones in the disease. A better understanding of hormones' pathophysiologic role in HS would improve our ability to use targeted therapies for hormonally driven disease. Psychological and psychosexual support is an important aspect for women with HS as part of any disease-management strategy. This article combines the most recent pathogenic and mechanistic findings with evidence-based clinical management to improve care for women with HS.
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