肝臓学と膵臓科学

Exploring the Molecular Mechanisms of Hepatic and Pancreatic Diseases

Abstract

Jaehyun Lee

Hepatic and pancreatic diseases pose significant challenges to human health worldwide. Understanding the underlying molecular mechanisms of these diseases is crucial for the development of effective diagnostic methods, therapeutic interventions, and potential cures. This article aims to delve into the intricate molecular pathways involved in hepatic and pancreatic diseases, shedding light on the current research and highlighting the promising areas of investigation. The liver plays a central role in metabolism, detoxification, and the synthesis of essential proteins. Several molecular mechanisms contribute to the development of hepatic diseases, including viral infections (such as hepatitis B and C), alcohol-induced liver disease, Non-Alcoholic Fatty Liver Disease (NAFLD), and Hepato Cellular Carcinoma (HCC). In viral hepatitis, the viral particles directly target hepatocytes, leading to inflammation, cellular damage, and liver dysfunction. NAFLD, on the other hand, involves complex interactions between genetic predisposition, environmental factors, and metabolic abnormalities.