バイオセラミックスの開発と応用

Improvement of Mechanical Properties of 3d Printed Hydroxyapatite Scaffolds by Polymeric Infiltration

Abstract

Stevanovic S, Chavanne P, Braissant O, Pieles U, Gruner P and Schumacher R

Tailor made bioceramic scaffolds in combination with the corresponding surface chemistry and biology is of great importance for a successful implantation and rapid osseo-integration. The present study investigates the fabrication of Hydroxyapatite (HA) scaffolds with defined macro porosity by means of powder based 3D-printing. In order to mime natural bone with its elastic collagen structure, the 3D-printed ceramic structures were post-treated by polymeric infiltration. Compressive Strength analysis (CS) confirmed the positive impact of an elastomeric phase on mechanical properties. 3D-printed HA scaffolds in combination with polymer result in biodegradable scaffolds with promising mechanical properties for potential use in regenerative medicine.