スポーツ医学およびドーピング研究ジャーナル

Alzheimer′s disease and Aerobic Exercise

Abstract

Juerie Baker

Observational evidence in humans suggests higher levels of cardiorespiratory fitness and physical activity are associated with greater brain volume, less brain atrophy, slower dementia progression, and reduced risk of dementia. Increased cardiorespiratory fitness also attenuates the detrimental effects of cerebral amyloid on cognition. Randomized controlled trials of aerobic exercise (AEx) in individuals with mild cognitive impairment (MCI) and subjective memory complaints have found exercise improved cognitive function. Aerobic exercise is a low-cost, low-risk, widely available intervention that may have disease-modifying effects. Aerobic exercise offers a low-cost, low-risk, widely available intervention that may have disease-modifying effects.