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細胞学および組織学ジャーナル

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音量 14, 問題 5 (2023)

ミニレビュー

Histopathology and Personalized Medicine: Tailoring Treatment Strategies

Arsalan Ahmed*

Histopathology plays a pivotal role in the era of personalized medicine, where treatment strategies are increasingly tailored to individual patients. This article explores the convergence of histopathology and personalized medicine, highlighting the significance of histopathological analysis in guiding patient-specific treatment plans. We delve into the evolving landscape of personalized medicine and the diverse techniques and technologies that are revolutionizing the field of histopathology. Histopathology, Personalized medicine, Precision medicine, Treatment strategies, Biomarkers, Molecular diagnostics. In some cases, obtaining adequate tissue samples for histopathological analysis can be challenging, especially in metastatic or recurrent cancers.

ミニレビュー

The Impact of Immunohistochemistry in Histopathological Diagnosis

Janiklas Minky*

Histopathological examination is a fundamental tool in the diagnosis and prognosis of various diseases, including cancer. Traditional histopathology relies on the visual analysis of tissue samples, often accompanied by stains that highlight specific features. However, this method has limitations, especially when distinguishing between different tissue types and subtypes. Immunohistochemistry (IHC) has revolutionized histopathology by introducing the use of antibodies to detect specific proteins within tissues. This article explores the significant impact of immunohistochemistry in histopathological diagnosis, discussing its principles, applications, advantages, and challenges.

解説

Histopathology in Oncology: Unraveling the Secrets of Tumor Microenvironments

Jinlu Liu*

Histopathology, the study of tissue at a microscopic level, has long been a cornerstone of oncology. It has played a crucial role in cancer diagnosis, prognosis, and treatment planning. However, recent advancements in the field have enabled histopathologists to delve even deeper into the intricacies of cancer biology by examining the tumor microenvironment. This article explores the significance of histopathology in understanding the complex interactions within the tumor microenvironment, shedding light on the secrets that hold the key to more effective cancer therapies.

視点

Exploring the Future of Histopathology: Innovations and Breakthroughs

Dardo Menditti*

Histopathology, the microscopic examination of tissue samples to diagnose diseases, has been a cornerstone of modern medicine for over a century. While the fundamental principles of histopathology have remained largely unchanged, the field is on the cusp of a revolutionary transformation. In this article, we explore the innovations and breakthroughs shaping the future of histopathology, from digital pathology and artificial intelligence to advanced imaging techniques and personalized medicine.

短報

Histopathological Approaches for Neurological Disorders: Current Insights

Tejas Bajwa*

Neurological disorders encompass a wide range of conditions that affect the central and peripheral nervous systems, often leading to significant disability and reduced quality of life. Histopathological techniques have played a crucial role in understanding the underlying mechanisms of these disorders. This article provides an overview of current insights gained through histopathological approaches in studying neurological disorders.

短いコミュニケーション

Histopathology in Veterinary Medicine: Advancements and Applications

Verena Habermaass*

Histopathology is a fundamental discipline in veterinary medicine that has undergone remarkable advancements in recent years. This article explores the evolving landscape of histopathology in veterinary medicine, focusing on the latest technologies, applications, and their impact on animal healthcare. We also discuss the importance of histopathology in disease diagnosis and treatment, highlighting the crucial role it plays in improving the overall well-being of animals.

研究論文

Detailed analysis of lymphatic invasion using D2-40 immunostaining in early gastric adenocarcinoma: Proposal of the classification of lymphatic invasion by D2-40 immunostaining

Toshiharu Matsumoto* and Kanako Ogura

Aims: Lymphatic invasion by D2-40 immunostaining has been evaluated based on the presence of carcinoma cells in the lymphatic lumen, but the entering of carcinoma cells with an invading style into the lymphatic lumen of a lymphatic vessel was reported in early gastric adenocarcinoma (EGAC), in which carcinoma cells localize within mucosa or submucosa. Here, a detailed examination of lymphatic invasion by D2-40 immunostaining is made in EGAC. Methods: A total of 204 EGAC patients who underwent endoscopic submucosal dissection was examined. Lymphatic invasion was classified as intra-lumen type and invading type by D2-40 immunostaining. In the intra-lumen type, carcinoma cells are present in the lymphatic lumen. In the invading type, carcinoma cells invade the lymphatic vessel with destruction of the lymphatic wall and enter the lymphatic lumen.

ミニレビュー

Emerging Trends in Histopathology Techniques for Disease Detection

Ping Lei*

Histopathology has long been a cornerstone of disease diagnosis and prognosis, enabling healthcare professionals to examine tissue samples for abnormalities and pathological changes. In recent years, the field of histopathology has seen remarkable advancements, driven by innovative techniques and technologies. This article explores emerging trends in histopathology techniques for disease detection, covering topics such as digital pathology, Artificial Intelligence (AI) integration, multiplexed assays, and tissue engineering. These trends are reshaping the landscape of histopathology, offering improved accuracy, efficiency, and diagnostic insights, ultimately leading to better patient care.

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