人類遺伝学と発生学

Toward Live Longer, Younger, Happier and Healthier: Reprogramming for a New Start or Just a Turn?

Abstract

Yue Zhang Msup

Whether we could live longer, younger, happier, and healthier as well as especially cancer-free in the future? Reprogramming in stem cell therapy and regenerative medicine could shed light on it. Whether the DNA of the mature cell still hold all the information needed to develop all cells in the organism? 50 years ago, most if not all biologists could have said “no.” However, Sir Gurdon applied his frog nuclear tranplantation (cloning) to say “yes”, it thus is feasible with one reprogramming for a new start i.e. the specialisation of cells is reprogrammable. At that time, he even predicted that the mammalian animal cloning would come up during following 50 years. In fact, one of most fascinating events is the Dolly cloning around the turn of this century.