人類遺伝学と発生学

The Molecular Mechanisms of Retinoic Acid Receptor Signaling

Abstract

Ferino James*

Retinoic Acid Receptors (RARs) are nuclear receptors that play pivotal roles in various physiological processes, including development, differentiation, and homeostasis. This review explores the intricate molecular mechanisms underlying RAR signaling, focusing on receptor structure, ligand binding, regulator interactions and downstream transcriptional regulation. By delving into the details of RAR signaling, we aim to provide a comprehensive understanding of how these receptors contribute to cellular responses and their implications in health and disease.