人類遺伝学と発生学

Selectivity studies of the drug fs-1 in mixture of eukariotic and microbial cells

Abstract

Sholpan Tursunova

A comparative study of the degree of influence of a drug being developed on microbial and eukaryotic cells is one of the important stages in the drug development.

This study examined the selective effect of a novel drug FS-1 on bacterial cells in the presence of eukaryotic cells.

The drug FS-1 is a nanocomplex of iodine and lithium and magnesium halides with dextrin and polypeptides, the molecular weight of dextrin enables penetration of active centers of the FS-1 molecule into the cells. Mycobacterium smegmatis ATCC 607 was used as a model system.

Data were obtained that indicate the effect of FS-1 predominantly on bacterial cells.