血液とリンパのジャーナル

小児急性リンパ性白血病の予後マーカーとしての BIRC5 遺伝子の役割

Abstract

Al-Sharkawy E?Ghobrial AG?Eldin AMK?Sabre MM?Aboul-Fotoh LE???? El-Deen HTG

?????:????????? (ALL) ??????????????????????????????????????????? (BIRC5) ??????????????????????????? (IAP) ??? Survivin ??????????????????????????????????????????????????????????? ALL ???? BIRC5 ???????????????????
?????:?????2 ????????? 42 ?? novo ALL ??????????????? 10 ??????????? (???) ??????????????????????????????CBC?????????????????????????LDH?????BM?????????????????????????????????????????ALL???????BM??????????????????????PCR???BM????????????????????????????????????
??? ALL???????????????BIRC5?????????P=0.0004??????BALL?????B-ALL????????T-ALL??????????????????????????P=0.001??????????LDH????????WBC???????????????????????r=0.47?P=0.002?r=0.31?P=0.05?r=0.62?P=0.001???????????????????????LDH?WBC???????????????????ALL???94.5?????????????????????????ALL?????????????????25??????P=0.001??
??? BIRC5????????ALL??????????????????????BIRC5??????????????????ALL???????????????????