Ramalingam K
Cancer being a multistep, and multi profile disease of multiple etiology, the complete cure for this emperor disease is out of reach in clinical oncology, in spite of multifarious drugs and innovative modalities of treatment procedures. Even the most successful chemotherapy is unable to cure the stage 3&4 cancer wherein the cancer cells take up the metastatic profile and migrate to keep away from the primary site to distinct organs and settle by immune- compromisation to seed and breed the secondary population of cancer cells which differ from their primary progenitor cells in various aspects.
Metastatic cancers until this hour remain as incurable especially in breast cancer patients with currently available therapies. Research investigation using cell lines and clinical studies are hectically striving to find cures for such IIIrd and IVth slater stage cancers or resistant cancers permanently and to prevent the disease relapse. The perusal of the results of some case studies in women revealed that both surgical ablation and chemotherapeutic intervention proved futile and instead of palliating the patient’s health condition, they drove the patients to fatal ending due to aggressive invasion of metastatic cells consequent to invasive surgery from the primary site to such vital organs as brain, lung and liver and the consequent collapse.
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