María Josefa
DNA methylation, an epigenetic modification crucial for gene regulation, exhibits remarkable heterogeneity across different tissues, developmental stages and individuals. This mosaic-like pattern of methylation plays a pivotal role in cellular identity, differentiation and disease susceptibility. Understanding the intricacies of this heterogeneity offers insights into fundamental biological processes and opens avenues for therapeutic interventions. This review delves into recent advancements in elucidating the complex landscape of DNA methylation mosaic, highlighting its implications in health and disease.
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