腎臓学と治療学ジャーナル

Bedside Alarmin: Neutrophil-to-Lymphocyte Ratio in Acute Kidney Injury

Abstract

Devrim Bozkurt*,Dilara Kilic,Tugba Kip,Mehmet Berktas,Kilavuz Asli,Akcicek Fehmi

mphocyte ratio (NLR) is novel prognostic marker in various inflammatory conditions. We performed a retrospective study investigating whether NLR has prognostic significance in patients suffered from AKI. Materias and Methods: Two hundred and ninety five AKI patients were evaluated retrospectively. Baseline values on admission, final values at discharge and after discharging during follow-up period in outpatient clinic until six months to one year were recorded. Results: It has been shown that, final NLR and timely changed NLR during hospital course are significant mortality predictors in AKI patients both in univariate and mutually adjusted multivariate logistic regression analysis. To predict mortality, we showed that, level of 9.90 point for final NLR has 73% sensitivity and 87% specifity as compared to value below in ROC analysis (HR: 7.31, CI 3.36-15.91; p < 0.001). Conclusion: NLR can be a novel screening tool for AKI patients during their hospital course