腫瘍外科アーカイブ

Multicentric Castleman's Disease (MCD) is a rare and poorly understood disorder that straddles the intersections of hematology, oncology, rheumatology, and virology and can be fatal if improperly treated. The etiology of HHV8 negative disease is unknown and only isolated cases of associations with infectious agents have been reported in literature. However the co-occurrence of Mycobacterium cosmeticum with Castleman’s disease has never been previously reported in literature. Hence we would like to report a case of Multicentric Castleman’s disease with a coexisting M. cosmeticum infection.

Mario Milletti (1914-1959) was a pioneer of modern neurosurgery in Italy, one of the founders of the Italian Society of Neurosurgery in 1948. In this work the Author emphasizes the Milletti’s contributions to brain tumors, which were important both from a diagnostic aspect and as regards the operating case studies. Especially significant was his study, published in Acta Neurochirurgica in 1950, on the angiographic differential diagnosis of different histological types.

Many of the diseases can cause severe neck pain in older patients. 10% of people will have neck pain in a life time. The most common causes are axial pain, whiplash-associated disorder, and cervical radiculopathy. Most cases without trauma, motor and/or sensory changes, and radiological abnormalities were diagnosed as axial pain. To date, crowned dens syndrome (CDS) and acute calcific retropharyngeal tendinitis (ACRT) have been almost considered as the main causes of acute neck pain in the elderly without trauma.

Preventing mastectomy (or prophylactic or risk reducing mastectomy) has been a major area of interest within the field of surgical methods during the last years, as a result of the recognition that the genetic basis of patients with BRCA 1 and 2 mutations, and those with very strong family history, acts as an indicative factor. Whereby, the procedure appears to be a cancer disease preventing method at very high risk patients.

Firstly, surgical management of Preventing Mastectomy and Implant Based Reconstruction is easier in small and moderate ptotic breasts, rather than in big and extensive breasts. Whereas, in patients with macromastia a reduction or mastopexy procedure is needed in order to achieve the desirable shape and position of the breast. In this category of patients viability and survival of Nipple Areola Complex is unsecure. Thus, this technique describes the performance of Preventing Mastectomy using a three pedicle dermal flap that supports blood supply of the NAC and increases the survival rate. All patients who underwent the three pedicle technique had been operated at the Plastic Surgery Department of Nicosia General Hospital between October of 2013 and October of 2015, by the writer.