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統合腫瘍学ジャーナル

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The Susceptive Probability: Lymphoma in Immune Deficiency

Abstract

Anubha Bajaj

The premise of immune surveillance was scripted by Burnet. The theory declares that the immune system may demonstrate a capacity to recognize and eradicate nascent and contemporary malignancies. Tumefaction may be generated by the cells of a particular organism or homo-sapiens which represent as specific antigens identifiable by the immune system. Individuals with a poor or defective immune system may engender subcategories of malignancy. The White Blood Corpuscles (WBCs) identify and ineffectively eliminate tumor cells in immune compromised subjects, in contrast to immune competent persons. Numerous immune procedures are implicated for malignant conversion with a primary immune deficiency such as enhancement and manifestation of immune cells, viral infections, modifications and reactivity to bone marrow tissue and chronic inflammation. The incidence of emerging lymphoma is augmented in congenital and acquired immune deficiency. Chronic antigenic stimulation incited by the oncogenic viruses and a lack of appropriate "antibody feedback mechanism" cogitating the lymphoid proliferation elevates the percentage of quantifiable lymphoid malignancies.

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