コンピュータサイエンスとシステム生物学のジャーナル

Study of Left Ventricle Pressure-Volume Loops in Renal Stenosis Case Using Equivalent Electrical Circuit

Abstract

Mona Abdolrazaghi, Mahdi Navidbakhsh, Kamran Hassani and Farhad Izadi

In this study, we have obtained the cardiac pressure-volume graphs of Renal Artery Stenosis disease with different stenotic values, moreover, the graphs are compared with normal condition. The cardiovascular Electronic circuit includes 42 elements including main arterial vessels. We have extracted the vessels geometrical data from the medical texts. The calculated pressure drops and the compliance variations of artery stenosis are applied to the electronic model. Then, the graphs have been obtained for different stenotic values (20%, 50%, 70%, and 90%) using ORCAD/ MATLAB software. Finally, the results of modeling have been discussed and compared with the clinical data. The results of stenosis show that hypertension could be a symptom of the disease. When the rate of stenosis increases the blood pressure rises. This study is a tool for students in order to see the cardiovascular system operation in normal condition or abnormal.