臨床症例報告ジャーナル

Recurrent Attacks of Myoclonus in an Old Man Taking Sildenafil.

Abstract

Kyoo Ho Cho, Kyoung Heo, Su Jin Chung, Yang-Je Cho and Byung In Lee

Sildenafil, a medication for treatment of erectile dysfunction, is commonly used these days. Its side effect in nervous system such as seizure and myoclonus are known to be rare. A 74-year old man developed multifocal myoclonus 12 hours after taking sildenafil. Electroencephalography (EEG) showed spike discharges and on the other day. The symptom resolved two days after, and spike discharges on EEG also disappeared. 8 years before, he had experienced the same symptom after taking sildenafil. We report a case of myoclonus as a possible side effect of sildenafil and the EEG finding suggests that myoclonus associated with sildenafil is of cortical origin.