外科ジャーナル

Plasma Cell Mastitis-Anatomo-Clinical and Therapeutic Considerations

Abstract

Roxana Maria Livadariu, Radu Danilă, Daniel Timofte, Delia Ciobanu and Corneliu Diaconu

Introduction: Plasma cell mastitis is a rare chronic inflammatory disease of the breast. Its cause and treatment have not yet been clearly identified. The aim of the study is to present the author's experience with various treatment methods applied on this disease.

Materials and Methods: We retrospectively analyzed the clinical findings, biological tests, imagistic results, therapeutic approach and the pathological response from 25 patients diagnosed with plasma cells mastitis between 2005 and 2013.

Results:  Only 7 cases underwent from the beginning to wide surgical excision of the inflammatory mass with favorable evolution. The rest of the patients, treated with antibiotherapy, corticotherapy or surgical drainage of the collections (when needed) presented early relapse that required surgical treatment: large excision to subcutaneous mastectomy.

Conclusion: Surgical treatment represented by wide excision going up to subcutaneous mastectomy is the most effective therapeutic method for this benign, but with high relapsing potential, disease. It also has the advantage of giving a more accurate positive and differential diagnosis, most important with breast carcinoma.