微生物病因学ジャーナル

Pathogen-Induced Proteases: Dual Roles in Host Defense and Tissue Damage

Abstract

Renier Shabab

Pathogen-induced proteases play a critical role in the host's immune response to invading pathogens. These enzymes are secreted by immune cells and target proteins on the pathogen's surface, aiding in its clearance. However, dysregulated production of pathogen-induced proteases can lead to tissue damage and chronic inflammation. Therefore, understanding the regulation of these enzymes is essential for developing effective therapeutic strategies for infectious and inflammatory diseases. This mini-review provides an overview of the concept of pathogeninduced proteases and their role in the immune response.