臨床症例報告ジャーナル

Neuro Endocrine Breast Tumor: Primary or Secondary Tumor? Case Report and Review of the Litterature

Abstract

Debbagh A, Allaoui M, Alaoui Slimani K, Sbitti Y, Bennani F, Ichou M and Errihani H

Background: Neuroendocrine breast tumors may be primary or secondary with a fairly rare frequency; The diagnosis is based on the results of the pathological findings and the characterization between the primary and secondary origin is guided by the data of radiology (echomammography), the pathological and immunohistochemistry examinations as well as the data reported by the octreoscanner. Case presentation: We describe here a case of a 70-year-old patient who had a dorsal pain for six months. A Scan of rachis showed a tumoral process of the vertebral body of D2 extending intramedullarily. The realization of a thoraco abdomino-pelvic CT scan as part of an assessment of extension, revealed the presence of a left mammary nodule with diffuse liver metsatases. Liver and breast biopsy evoking a localization of a neuroendorin tumor. Conclusion: This presentation reveals that the Differentiation between primary or secondary neuro endocrine breast tumor is based on the results of the pathological, immunohistochemical findings and radiological characteristics. In the absence of a generalized metastatic disease, the treatment is similar to Invasive breast tumors, under metastasis conditions. The treatment consists of various therapetical modalities including chemotherapy, hormonotherapy targeted therapies.