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Laryngeal Adenoid Cystic Carcinoma-A Case Report and Review of Literature

Abstract

Jakub Pachla, Malgorzata Czesak, Ewa Osuch Wojcikiewicz, and Kazimierz Niemczyk

Objectives: Adenoid Cystic Carcinoma (ACC) is an extremely rare malignant neoplasm of the glandular tissues. In this article, we present a case of ACC in the larynx along with its clinical, pathological and therapeutic aspects. Methods: A 53-year-old man presented with suspected laryngeal ACC. Diagnostic tests were performed, including computed tomography and magnetic resonance imaging. Due to its clinical advancement, T4aN0 was qualified for surgical treatment. Results: Complete laryngectomy was performed with removal of the lobe of the thyroid on the right and selective cervical lymph node removal on the right, and formation of a tracheopharyngeal fistula with implantation of a voice prosthesis. Due to the type of malignant tumor and the degree of local advancement, the patient underwent complementary radiotherapy to the area of the laryngeal bed and regional lymph nodes, bilaterally. Twenty-four months after surgery, the patient remains disease-free. Conclusion: ACC constitutes less than 1% of all head and neck tumors. It is a highly aggressive malignancy with a high rate of recurrences and a tendency towards distant metastases. Currently, surgical resection with adjuvant radiotherapy is the gold standard in ACC treatment. Long-term follow up is required in ACC patients.

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