臨床症例報告ジャーナル

Isolated Metastasis of Uterine Leiomyosarcoma to the Small Bowel Diagnosed Initially as Uterine Leiomyoma: A Case Report and Review of the Literature

Abstract

Semmar A, Mouden K, Laanaz S, ELallam O, Kabdani T, Elkacemi T, Majjaoui SEL and Benjaafar N

Introduction: Uterine sarcoma is rare, Leiomyosarcoma is the main type of sarcoma that may resemble to leiomyoma. Metastasis to small bowel is extremely rare, treatment is chemotherapy and the prognosis is unfavorable.

Case presentation: A 41-year-old Moroccan women, with no significant past medical history, was diagnosed with intracavitary myoma. The patient underwent subtotal hysterectomy with bilateral salpingectomy. Pathology findings indicated high grade leiomyosarcoma. The patient was re-operated, she underwent bilateral oophorectomy, omentectomy, segmental small bowel resection and excision of uterine cervix. Histopathology revealed a metastatic lesion of the primary uterine leiomyosarcoma of the small bowel. The patient was treated by chemotherapy: Doxorubicin 75 mg/m2 every 3 weeks for 6 cycles. The follow-up of this patient is 10 months and her ECOG is 0.

Conclusion: Leiomyosarcoma is the main type of sarcoma that may resemble to leiomyoma. Metastatis to small bowel is rare, treatment is chemotherapy and the prognosis is poor.