臨床症例報告ジャーナル

Is Hypertrophic Osteoarthropathy Associated with Smoking?

Abstract

Babu Philip, Sandhya Limaye, Thanakrishnan G and Arun Aggarwal

Hypertrophic Osteoarthropathy (HOA) is a disease of the joints and bones characterized by advanced clubbing that is bulbous enlargement of the ends of one or more fingers or toes; proliferation and oedema of connective tissue resulting loss of the normal angle between the skin and nail, excessive sponginess of the nail base of the digits of the hands and feet. There is painful periosteal proliferation of long bones such as the radius, ulna, or tibia in clubbing, and the periostitis is often associated with mild fever and arthralgia or joint effusion. There are two accepted types of HOA, primary and secondary. The former is usually inherited and hereditary (idiopathic), while the secondary type seen as a concurrent manifestation of another diseases. Herein, we present a 23-year-old man diagnosed with primary HOA and had only smoking history. After examining the patient, we have concluded that there is possibility of relationship between the HOA and smoking history.