介入および一般心臓学ジャーナル

Heart Failure is a Clinical Syndrome Marked by Common Symptoms

Abstract

Johann Bauersachs*

The prevalence of heart failure, a clinical syndrome characterized by common symptoms, is rising globally annually. Malnutrition, obesity, and the annual rise in diabetes mellitus are among these factors. Others include an increase in alcohol consumption, smoking, high blood pressure, and other risk factors. The pathophysiology of chronic heart failure includes a complex array of circulatory and neurohormonal system issues that contribute to the onset of stationary symptoms. The vasodilator and vasoconstrictor neurohormonal systems are in balance in generally healthy individuals. In the pathophysiology of chronic heart failure, a variety of circulatory and neurohormonal system issues play a role in the onset of stationary symptoms. Vasodilator and vasoconstrictor neurohormonal frameworks are in balance in basically solid people. The activity of natriuretic peptides, particularly BNP, causes numerous significant effects on the heart and kidney. Reduced arterial blood pressure, vasodilation, increased diuresis and natriuresis, increased soft tissue filtration, decreased renin and aldosterone secretion, antihypertensive and antifibrotic effects, lipolysis, and mitochondrial biogenesis are among the organism's physiological effects of natriuretic peptides.