臨床症例報告ジャーナル

Fulminant Hepatic Failure Resulting from Coexistent Wilson’s Disease, Hepatitis E and Herbal Medication: A Case Report

Abstract

Baliga Kiran, Pradyum Ram, Baliga BS, Rajesh SM and Kini Prashant

Infection with hepatitis A virus can cause severe or even fatal illness in patients with chronic liver disease. Here we describe a ten-year-old girl who presented as acute liver failure and was diagnosed with Wilson’s disease and later with coexistent hepatitis E infection. Wilson’s disease was demonstrated on the basis of Kayser Fischer ring, low ceruloplasmin, and high urinary copper excretion. Hepatitis E was diagnosed serologically with a positive anti HEV IgM titers. Our case suggests that acute hepatitis E may play a part in the acute decompensation seen in some cases of unrecognized Wilson’s disease. The patient gradually deteriorated and died in a period of 3 months.