抗菌剤ジャーナル

Empiric Antibiotic Regimens and the Incidence of Acute Kidney Injury in Hospitalized Black Patients

Abstract

Andrew A Yabusaki*

The selection of inpatient empiric antibiotic regimens is a significant challenge for hospitalists and clinicians today. Much is known about the increased incidence of acute kidney injury associated with the use of vancomycin and piperacillin-tazobactam in combination compared to vancomycin and other beta-lactam combinations. What is less clear is the incidence of antibiotic associated acute kidney injury and outcomes in Black patients. Incidence rates of acute kidney injury are already known to be higher in Black patients compared to white patients, which makes extrapolating the risks of antibiotic associated acute kidney injury challenging. In addition, only one research paper has included a study population with greater than 50% Black patients.