外科病理学および診断ジャーナル

Donor Characteristics in Graft Detachment after Posterior Lamellar Keratoplasty

Abstract

Lisa Sandra*

Posterior Lamellar Keratoplasty (PLK), including Descemet's stripping automated endothelial Keratoplasty and Descemet's Membrane Endothelial Keratoplasty (DMEK), has revolutionized the treatment of corneal endothelial diseases. Despite its high success rates, graft detachment remains a significant complication, affecting visual outcomes and necessitating re-grafting in some cases. This article delves into the donor characteristics associated with graft detachment after PLK, exploring various factors such as donor age, endothelial cell density, graft preparation techniques, and surgical expertise. Understanding these factors is crucial for optimizing graft selection and surgical outcomes in PLK procedures. Posterior Lamellar Keratoplasty (PLK) has emerged as the standard of care for treating corneal endothelial disorders. While the technique offers numerous advantages over traditional penetrating keratoplasty, graft detachment remains a challenging complication that affects visual outcomes and graft survival. Graft detachment occurs due to various factors, including donor characteristics. This article aims to review the literature on donor characteristics influencing graft detachment after PLK, providing insights into optimizing donor selection and surgical techniques.