Zhenhua He
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease and the care of patients with diabetes and DN contributes significantly to health care costs. Of patients with type 1 diabetes, approx 20%-30% will eventually develop DN, whereas about 10%-20% of those with type 2 diabetes will do so. In the past couple of decades, there have been notable advances in our knowledge regarding the DN, including the advent of interventions that can significantly slow or even reverse the course of progressive disease. This review describes the definition and detection of diabetic kidney disease, its natural history, current proven therapies, and potential future therapies.
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