介入および一般心臓学ジャーナル

Cardio Protective Mechanisms against Reperfusion Injury in Acute Myocardial Infarction: Targeting Angiotensin II Receptors

Abstract

Nicholas Teman*

Acute Myocardial Infarction (AMI) is a life-threatening condition characterized by the sudden interruption of blood flow to the heart muscle, leading to tissue damage and potentially fatal outcomes. Reperfusion therapy, aimed at restoring blood flow to the affected area, is the primary intervention for AMI. However, paradoxically, the process of reperfusion itself can induce additional injury, known as reperfusion injury. Understanding the underlying mechanisms of reperfusion injury is crucial for developing effective cardio protective strategies. This article explores the role of angiotensin II receptors in reperfusion injury and discusses potential therapeutic interventions targeting these receptors for cardioprotection in AMI.