生物工学および生物医学科学ジャーナル

Bioengineering Approaches to Female Infertility

Abstract

Pamela Kreeger

Chemotherapy, uterine injuries, fallopian tube occlusion, massive intrauterine adhesions, congenital uterine malformations and hysterectomy have all been shown to have a significant impact on female infertility and bioengineering techniques have shown great promise in this regard. The following are two broad categories that apply to these strategies: I) Transplantation of new or cryopreserved organs into the host and (ii) tissue designing methodologies that use a mix of cells, development factors and biomaterials that use the body's inborn capacity to recover/fix conceptive organs. The source of the organ and the immunogenic effects of allografts remain challenging despite whole organ transplant's success. Tissue engineering techniques can avoid these problems, but they haven't been shown to be effective at creating whole organ structures. We present a synopsis of the most recent developments in the treatment of female infertility using bioengineering.