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Appendiceal Adenoma on F-18 FDG PET-CT in a Patient with Hodgkin Lymphoma: A Case Report and Literature Review

Abstract

Nicole A Lamparello, Kenneth B Hymes, Bedros Taslakian and Roy A Raad

Appendiceal tumors including adenocarcinoma and carcinoid are rare, accounting for less than 1 percent of appendectomy pathology specimens. Adenomas of the appendix are even more rare, with an incidence of less than 0.2 percent. By definition, appendiceal adenomas (cystadenoma, villous adenoma, etc.) are benign tumors confined to the muscularis mucosa layer without invasion. Although the gastrointestinal tract is the most common site for extranodal non- Hodgkin lymphoma, lymphomatous infiltration of the appendix is uncommon with a frequency of 1%-3%. Furthermore, Hodgkin lymphoma, rarely involves extra-nodal sites. Knowledge of the different patterns of extranodal lymphoma manifestations is important when analyzing foci of metabolic uptake on F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT).

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