コンピュータサイエンスとシステム生物学のジャーナル

Analogue Computer Model of Progressive Myopia-Refraction Stability Response to Reading Glasses

Abstract

Peter R. Greene and Antonio Medina

A tendency of the eye to become myopic with long hours focusing at a near distance has been reported often [1-8]. Myopia development, as any refractive development, is described by a first order feedback system. A first order feedback system is defined by its transfer function F(s) = 1/(1+ks) [1,2]. This function anticipates an exponential development of refractive state and the effect of lenses. Near work is myopizing, as it is equivalent to wearing a negative lens. Using a digital computer, first-order equations have been solved previously to describe and predict myopia progression [1,3]. An analogue circuit can simulate myopia progression vs. time R(t) because the response of the feedback system is the same as the capacitor voltage in a R-C (Resistor-Capacitor) circuit, as shown in Figure 1. When near work is involved a negative square-wave represents the daily accommodative demand as represented in the inset in Figure1[3]. The R-C circuit solves the problem without any computations.